BIOL 111 Table 6.1

From Notes
Jump to navigation Jump to search

The Structure and Function of the Cytoskeleton

Property Microtubules (Tubulin Polymers) Microfilaments (Actin filaments) Intermediate Filaments
Structure Hollow tubes; wall consists of 13 columns of tubulin molecules Two intertwined strands of actin, each a polymer of actin subunits Fibrous proteins supercoiled into thicker cables
Diameter 25nm with 15nm lumen 7nm 8–12nm
Protein Subunits Tubulin, a dimer consisting of α-tubulin and β-tubulin Actin One of several different proteins of the keratin family, depending on cell type
Main functions
  • maintenance of cell shape (compression-resisting "girders")
  • Cell motility (cilia or flagella)
  • Chromosome movements in cell division
  • Organelle movements
  • Maintenance of cell shape (tension-bearing elements)
  • Changes in cell shape
  • Muscle contraction
  • Cytoplasmic streaming
  • Cell motility (pseudopodia)
  • Cell division (cleavage furrow formation)
  • Maintenance of cell shape (tension-bearing elements)
  • Anchorage of Nucleus and certain other organelles
  • Formation of nuclear lamina